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Schizosaccharomyces pombe encodes a mutated AP endonuclease 1.

DNA repair - 7 Mar 2011

Laerdahl Jon K, Korvald Hanne, Nilsen Line, Dahl-Michelsen Kristin, Rognes Torbjørn, Bjørås Magnar, Alseth Ingrun

Abstract excerpt

Mutagenic and cytotoxic apurinic/apyrimidinic (AP) sites are among the most frequent lesions in DNA. Repair of AP sites is initiated by AP endonucleases and most organisms possess two or more of these enzymes. Saccharomyces cerevisiae has AP endonuclease 1 (Apn1) as the major enzymatic activity with AP endonuclease 2 (Apn2) being an important backup. Schizosaccharomyces pombe also encodes two potential AP...

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Identifiers

PMID: 21193357
DOI: 10.1016/j.dnarep.2010.11.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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