Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fission yeast Uve1 and Apn2 function in distinct oxidative damage repair pathways in vivo.

DNA repair - 21 Nov 2003

Fraser J Lee A, Neill Erin, Davey Scott

Abstract excerpt

In Schizosaccharomyces pombe, the endonuclease Uve1 functions as the first step in an alternate UV photo-product repair pathway that is distinct from nucleotide excision repair (NER). Based upon the broad substrate specificity of Uve1 in vitro, and the observation that Uve1 mutants accumulate spontaneous mutations at an elevated rate in vivo, we and others have hypothesized that this protein might have a function...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endodeoxyribonucleases
Share to Hydrogen Peroxide
Share to Oxidants

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Oxidation-Reduction

Share to Oxygen

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Share to Ultraviolet Rays

Source

Identifiers

PMID: 14599746
DOI: 10.1016/j.dnarep.2003.08.005

Genes

OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fission yeast Uve1 and Apn2 function in distinct oxidative damage repair pathways in vivo.PMID 14599746Read ↗

A Uve1p-mediated mismatch repair pathway in Schizosaccharomyces pombe.Semantic proximity Read ↗

The Uve1 endonuclease is regulated by the white collar complex to protect cryptococcus neoformans from UV damage.Semantic proximity Read ↗

Schizosaccharomyces pombe encodes a mutated AP endonuclease 1.Semantic proximity Read ↗

The activity of yeast Apn2 AP endonuclease at uracil-derived AP sites is dependent on the major carbon source.Semantic proximity Read ↗

A new Schizosaccharomyces pombe base excision repair mutant, nth1, reveals overlapping pathways for repair of DNA base damage.Semantic proximity Read ↗

The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae.Semantic proximity Read ↗

Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation.Semantic proximity Read ↗

Ddb1 controls genome stability and meiosis in fission yeast.Semantic proximity Read ↗

AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe.Semantic proximity Read ↗

Ntg1p, the base excision repair protein, generates mutagenic intermediates in yeast mitochondrial DNA.Semantic proximity Read ↗

Spontaneous mutation, oxidative DNA damage, and the roles of base and nucleotide excision repair in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

The activity of yeast Apn2 AP endonuclease at uracil-derived AP sites is dependent on the major carbon sourceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.