Article
Aod2, the locus controlling development of atrophy in neonatal thymectomy-induced autoimmune ovarian dysgenesis, co-localizes with Il2, Fgfb, and Idd3.
The Journal of experimental medicine - 1 Feb 1996
Teuscher C, Wardell B B, Lunceford J K, Michael S D, Tung K S
Abstract excerpt
In genetically susceptible strains of mice, such as A/J and (C57BL/6J x A/J)F1 hybrids, neonatal thymectomy-induced autoimmune ovarian dysgenesis (AOD) is characterized by the development of antiovarian autoantibodies, oophoritis, and atrophy. Temporally, atrophy may be observed during and after...
Topics
- Animals
- Animals, Newborn
- Atrophy
- Autoimmune Diseases
- Chromosome Mapping
- Diabetes Mellitus, Type 1
- Female
- Fibroblast Growth Factor 2
- Genetic Linkage
- Gonadal Dysgenesis
- Interleukin-2
- Male
- Mice
- Oophoritis
- Ovarian Diseases
- Ovary
- Phenotype
- Proteins