Article
A major linkage region on distal chromosome 4 confers susceptibility to mouse autoimmune gastritis.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 1999
Silveira P A, Baxter A G, Cain W E, van Driel I R
Abstract excerpt
Although much is known about the pathology of human chronic atrophic (type A, autoimmune) gastritis, its cause is poorly understood. Mouse experimental autoimmune gastritis (EAG) is a CD4+ T cell-mediated organ-specific autoimmune disease of the stomach that is induced by neonatal thymectomy of BALB/c mice. It has many features similar to human autoimmune gastritis. To obtain a greater understanding of the...
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