Article
SNPs upstream of the minimal promoter control IL-2 expression and are candidates for the autoimmune disease-susceptibility locus Aod2/Idd3/Eae3.
Genes and immunity - 1 Mar 2008
del Rio R, Noubade R, Subramanian M, Saligrama N, Diehl S, Rincon M, Teuscher C
Abstract excerpt
IL-2, a T-cell growth and differentiation factor, plays an important role in immune homeostasis. Previously, we identified IL2 as a candidate for Aod2, a quantitative trait locus (QTL) controlling susceptibility to autoimmune ovarian dysgenesis (AOD) induced by day 3 neonatal thymectomy. Here, we...
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