Article
Comparative genomic hybridization, allelic imbalance, and fluorescence in situ hybridization on chromosome 8 in prostate cancer.
Genes, chromosomes & cancer - 1 Nov 1994
Cher M L, MacGrogan D, Bookstein R, Brown J A, Jenkins R B, Jensen R H
Abstract excerpt
Due to problems with primary tumor cell culture, conventional cytogenetics has yielded little insightful information on chromosomal alterations in prostate cancer. The primary aim of this study was to define the ability of comparative genomic hybridization (CGH) to detect and map genetic deletions in prostate tumors. A secondary aim was to apply multiple assays to individual tumors as a means of deciphering the...
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