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Article

von Hippel-Lindau disease gene deletion detected in microdissected sporadic human colon carcinoma specimens.

Human pathology - 1 Feb 1996

Zhuang Z, Emmert-Buck M R, Roth M J, Gnarra J, Linehan W M, Liotta L A, Lubensky I A

Abstract excerpt

The progression of human malignancies is thought to involve the inactivation or loss of tumor suppressor genes. Previous studies have suggested that inactivation of tumor suppressor genes on chromosomes 5q, 17p, 18q, and 8p play a role in the development of colorectal carcinoma. However, chromosome 3p at the von Hippel-Lindau disease (VHL) gene locus (3p25-26) has not been previously implicated in the development...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 8617456
DOI: 10.1016/s0046-8177(96)90368-8

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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