von Hippel-Lindau disease gene deletion detected in microdissected sporadic human colon carcinoma specimens.

doi:10.1016/s0046-8177(96)90368-8

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Article

von Hippel-Lindau disease gene deletion detected in microdissected sporadic human colon carcinoma specimens.

Human pathology - 1 Feb 1996

Zhuang Z, Emmert-Buck M R, Roth M J, Gnarra J, Linehan W M, Liotta L A, Lubensky I A

Abstract excerpt

The progression of human malignancies is thought to involve the inactivation or loss of tumor suppressor genes. Previous studies have suggested that inactivation of tumor suppressor genes on chromosomes 5q, 17p, 18q, and 8p play a role in the development of colorectal carcinoma. However, chromoso...

Topics

Adenocarcinoma
Adenoma
Base Sequence
Chromosomes, Human, Pair 3
Colorectal Neoplasms
DNA, Neoplasm
Dissection
Gene Deletion
Genes, Tumor Suppressor
Heterozygote
Humans
Molecular Sequence Data
Mutation
Polymorphism, Single-Stranded Conformational
von Hippel-Lindau Disease

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PMID: 8617456
DOI: 10.1016/s0046-8177(96)90368-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8617456-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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