Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic deletion and mutation of the von Hippel-Lindau (VHL) tumor suppressor gene in pancreatic microcystic adenomas.

The American journal of pathology - 1 Oct 1997

Vortmeyer A O, Lubensky I A, Fogt F, Linehan W M, Khettry U, Zhuang Z

Abstract excerpt

An association between pancreatic microcystic (serous) adenomas (MCAs) and von Hippel-Lindau (VHL) disease has been suggested. However, genetic alterations of the VHL gene in MCAs of the pancreas have never been reported. In this study, we performed genetic analysis of 12 pancreatic MCAs. In 2 cases, VHL disease was documented clinically, and 10 cases were sporadic. For LOH analysis, tumor and normal pancreatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Deletion

Share to DNA, Neoplasm

Share to Genes, Tumor Suppressor

Share to Point Mutation

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 9327728
PMCID: PMC1858030

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic deletion and mutation of the von Hippel-Lindau (VHL) tumor suppressor gene in pancreatic microcystic adenomas.PMID 9327728Read ↗

Von Hippel-Lindau gene alterations in sporadic benign and malignant pheochromocytomas.Semantic proximity Read ↗

A novel pancreatic endocrine tumor suppressor gene locus on chromosome 3p with clinical prognostic implications.Semantic proximity Read ↗

Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma.Semantic proximity Read ↗

Associations between VHL genotype and clinical phenotype in familial von Hippel-Lindau disease.Semantic proximity Read ↗

Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors.Semantic proximity Read ↗

Differential Genetic Alterations in von Hippel-Lindau Syndrome-Associated and Sporadic Pheochromocytomas1Semantic proximity Read ↗

Somatic von Hippel-Lindau gene mutations detected in sporadic endolymphatic sac tumors.Semantic proximity Read ↗

Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype.Semantic proximity Read ↗

Molecular genetic analysis of the von Hippel-Lindau disease tumor suppressor gene in familial and sporadic cerebellar hemangioblastomas.Semantic proximity Read ↗

Detection of von Hippel-Lindau disease gene mutations in paraffin-embedded sporadic renal cell carcinoma specimens.Semantic proximity Read ↗

VHL inactivation is an important pathway for the development of malignant sporadic pancreatic endocrine tumors.Semantic proximity Read ↗

Comparison of epigenetic and genetic alterations in mucinous cystic neoplasm and serous microcystic adenoma of pancreas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.