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Article

Detection of the von Hippel-Lindau gene deletion in cytologic specimens using microdissection and the polymerase chain reaction.

Acta cytologica - 1 Jan 2000

Zhuang Z, Roth M J, Emmert-Buck M R, Lubensky I A, Liotta L A, Solomon D

Abstract excerpt

Previous studies have demonstrated von Hippel-Lindau (VHL) gene abnormalities in renal cell carcinoma. Archival cytologic samples of renal cell carcinomas (RCCs) from two patients were evaluated for allelic loss of the VHL gene. Small clusters of renal carcinoma cells were dissected from cytocent...

Topics

Alleles
Base Sequence
Carcinoma, Renal Cell
DNA, Neoplasm
Dissection
Gene Deletion
Heterozygote
Humans
Kidney Neoplasms
Microchemistry
Molecular Sequence Data
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

von Hippel-Lindau Disease

Source

Identifiers

PMID: 8091895

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8091895-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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