Article
Molecular analysis of the von Hippel-Lindau disease tumor suppressor gene in human lung cancer cell lines.
Oncogene - 1 Jun 1994
Sekido Y, Bader S, Latif F, Gnarra J R, Gazdar A F, Linehan W M, Zbar B, Lerman M I, Minna J D
Abstract excerpt
The deletion of the short arm of chromosome 3 is frequently observed in lung cancer. To determine whether the von Hippel-Lindau (VHL) disease tumor suppressor gene located at 3p25 is responsible for oncogenesis in lung cancer, we searched the known open reading frame using the single-strand confo...
Topics
- Base Sequence
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Genes, Tumor Suppressor
- Humans
- Lung Neoplasms
- Molecular Sequence Data
- Mutation
- Tumor Cells, Cultured
- von Hippel-Lindau Disease