Article
Presence of genetic alterations in microdissected stroma of human colon and breast cancers.
Journal of molecular medicine (Berlin, Germany) - 1 Jan 2000
Wernert N, Löcherbach C, Wellmann A, Behrens P, Hügel A
Abstract excerpt
We show by laser-assisted microdissection that frequent genetic alterations in non-hereditary invasive human colon and breast cancers (loss of heterozygosity and TP53 mutations) occur not only in the neoplastic epithelial cells, but also in the adjacent fibroblastic tumor stroma and that both com...
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