Article
Gene mutation analysis in non-small cell lung cancer patients using bronchoalveolar lavage fluid and tumor tissue as diagnostic markers.
The International journal of biological markers - 9 Dec 2014
Li Jian, Hu Yi-Ming, Wang Yi, Tang Xing-Ping, Shi Wei-Lin, Du Yong-Jie
Abstract excerpt
Non-small cell lung cancer (NSCLC) is one of the main causes of cancer death in the world. Early detection of NSCLC can improve its outcome. The aim of this study was to identify the mutations of the KRAS and p53 genes in bronchoalveoar lavage (BAL) fluid for the early detection of peripheral NSCLC. We examined the DNA obtained from the tumor, nearby normal lung tissue, and matched BAL fluid for mutations in the...
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