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Article

The 3' untranslated region of prohibitin and cellular immortalization.

Experimental cell research - 10 Apr 1996

Jupe E R, Liu X T, Kiehlbauch J L, McClung J K, Dell'Orco R T

Abstract excerpt

We have been studying the role of the evolutionarily conserved prohibitin gene in cellular immortalization and tumor suppression. Immortalized human cells are classified into four complementation groups (A, B, C, and D) based on the ability of fusion hybrids to become senescent. The present study...

Topics

Base Sequence
Cell Cycle
Cell Transformation, Neoplastic
Cells, Cultured
Fibroblasts
Genes, Tumor Suppressor
Humans
Molecular Sequence Data
Mutation
Prohibitins
Proteins
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Repressor Proteins

Source

Identifiers

PMID: 8612677
DOI: 10.1006/excr.1996.0120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8612677-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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