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Article

The 3' untranslated region of prohibitin and cellular immortalization.

Experimental cell research - 10 Apr 1996

Jupe E R, Liu X T, Kiehlbauch J L, McClung J K, Dell'Orco R T

Abstract excerpt

We have been studying the role of the evolutionarily conserved prohibitin gene in cellular immortalization and tumor suppression. Immortalized human cells are classified into four complementation groups (A, B, C, and D) based on the ability of fusion hybrids to become senescent. The present study expands our preliminary evidence showing that the antiproliferative activity of prohibitin is only effective in...

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Identifiers

PMID: 8612677
DOI: 10.1006/excr.1996.0120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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