Article
Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Aug 1997
Meno C, Ito Y, Saijoh Y, Matsuda Y, Tashiro K, Kuhara S, Hamada H
Abstract excerpt
BACKGROUND: Vertebrates have numerous lateral asymmetries in the position of their organs, but the molecular basis for the determination of left-right (L-R) asymmetries remains largely unknown. TGFbeta-related genes such as lefty and nodal are L-R asymmetrically expressed in developing mouse embr...
Topics
- Amino Acid Sequence
- Animals
- Carrier Proteins
- Chromosome Mapping
- Embryo, Nonmammalian
- Gene Expression Regulation, Developmental
- Glycoproteins
- Intercellular Signaling Peptides and Proteins
- Left-Right Determination Factors
- Mice