Article
Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.
Nature - 9 May 1996
Lowe L A, Supp D M, Sampath K, Yokoyama T, Wright C V, Potter S S, Overbeek P, Kuehn M R
Abstract excerpt
Vertebrates have characteristic and conserved left-right (L-R) visceral asymmetries, for example the left-sided heart. In humans, alterations of L-R development can have serious clinical implications, including cardiac defects. Although little is known about how the embryonic L-R axis is established, a recent study in the chick embryo revealed L-R asymmetric expression of several previously cloned genes,...
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