Article
p53 protein accumulation and gene mutations in multifocal esophageal precancerous lesions from symptom free subjects in a high incidence area for esophageal carcinoma in Henan, China.
Cancer - 1 Apr 1996
Wang L D, Zhou Q, Hong J Y, Qiu S L, Yang C S
Abstract excerpt
BACKGROUND: Multifocal occurrence of precancerous lesions of the esophagus has been observed among individuals in a high incidence area for esophageal carcinoma in Henan Province, China. Results from recent studies suggest that p53 protein accumulation and mutation occur early in the pathogenesis...
Topics
- Adult
- Aged
- China
- Esophageal Neoplasms
- Female
- Genes, p53
- Humans
- Immunohistochemistry
- Incidence
- Male
- Middle Aged
- Mutation
- Polymorphism, Single-Stranded Conformational
- Precancerous Conditions
- Tumor Suppressor Protein p53