Article
p53 immunoexpression: an aid to conventional methods in the screening of precursor lesions of squamous esophageal cancer in patients at high-risk?
Cancer detection and prevention - 1 Jan 2005
Fagundes Renato B, Melo Carlos R, Pütten Antonio C K, Moreira Luis F, de Barros Sérgio G S
Abstract excerpt
INTRODUCTION: Squamous cell carcinoma of the esophagus (SCCE) is diagnosed late and carries a poor prognosis. Lugol chromoendoscopy (LC) has being shown a useful tool in the management of patients at high risk for SCCE. Biomarkers such as p53 protein expression may be present in the esophageal mucosa long before esophageal symptoms or lesions appear and may aid in early diagnosis. This study was carried out to...
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