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Article

Dose-response relationship for mivacurium in patients with phenotypically abnormal plasma cholinesterase activity.

Acta anaesthesiologica Scandinavica - 1 Nov 1995

Ostergaard D, Jensen F S, Skovgaard L T, Viby-Mogensen J

Abstract excerpt

During thiopentone-fentanyl-nitrous oxide anaesthesia and using a cumulative design, we studied the dose-response relationship of mivacurium in 8 patients: 7 patients phenotypically homozygous for the atypical plasma cholinesterase gene and 1 patient homozygous for the silent gene. The estimated mean ED50 and ED95 were 15 and 20 micrograms.kg.bw-1 in patients homozygous for the atypical gene, and 13 and 16...

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Identifiers

PMID: 8607300
DOI: 10.1111/j.1399-6576.1995.tb04220.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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