Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pretreatment with pancuronium before suxamethonium administration in patients heterozygous for the usual and the atypical plasma cholinesterase gene.

Acta anaesthesiologica Scandinavica - 1 Aug 1991

Ostergaard D, Viby-Mogensen J, Hanel H K, Skovgaard L T

Abstract excerpt

The object of this study was to investigate whether pretreatment with pancuronium before i.v. injection of suxamethonium could cause prolonged neuromuscular blockade in patients heterozygous for the usual and the atypical plasma cholinesterase gene (E1uE1a). Forty-three patients, 23 with genotype E1uE1a and 20 with normal genotype (E1uE1u), were pretreated with pancuronium 0.01 mg.kg-1 followed by suxamethonium...

Topics

Adult
Aged
Cholinesterases
Female
Genotype
Heterozygote
Humans
Injections, Intravenous
Male
Middle Aged
Neuromuscular Junction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pancuronium

Succinylcholine

Source

Identifiers

PMID: 1897345
DOI: 10.1111/j.1399-6576.1991.tb03337.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1897345-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pretreatment with pancuronium before suxamethonium administration in patients heterozygous for the usual and the atypical plasma cholinesterase gene.PMID 1897345Read ↗

Mivacurium-induced neuromuscular blockade in patients with atypical plasma cholinesterase.Semantic proximity Read ↗

Pharmacokinetics and pharmacodynamics of mivacurium in patients phenotypically heterozygous for the usual and atypical plasma cholinesterase variants (UA).Semantic proximity Read ↗

Pharmacokinetics and pharmacodynamics of mivacurium in patients phenotypically homozygous for the atypical plasma cholinesterase variant: effect of injection of human cholinesterase.Semantic proximity Read ↗

Plasma cholinesterase and abnormal reaction to succinylcholine: twenty years' experience with the Danish Cholinesterase Research Unit.Semantic proximity Read ↗

Prolonged mivacurium neuromuscular block in children.Semantic proximity Read ↗

Response to mivacurium in a patient compound heterozygous for a novel and a known silent mutation in the butyrylcholinesterase gene: genotyping by sequencing.Semantic proximity Read ↗

Markedly prolonged paralysis after mivacurium in a patient apparently heterozygous for the atypical and usual pseudocholinesterase alleles by conventional biochemical testing.Semantic proximity Read ↗

Clinical importance of plasma cholinesterase for the anaesthetist.Semantic proximity Read ↗

Reaction to succinylcholine in two patients segregating for the plasma cholinesterase allele Ek.Semantic proximity Read ↗

Mivacurium sensitivity in a patient heterozygous for the atypical and silent genes for plasma cholinesterase.Semantic proximity Read ↗

Response to mivacurium in patients carrying the k variant in the butyrylcholinesterase gene.Semantic proximity Read ↗

[Plasma cholinesterase and abnormal reaction to suxamethonium injection. 20-year experience with the Danish Cholinesterase Registry].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.