Article
Clinical importance of plasma cholinesterase for the anaesthetist.
Annals of the Academy of Medicine, Singapore - 1 Nov 1994
Pedersen N A, Jensen F S
Abstract excerpt
Plasma cholinesterase is a glycoprotein synthesized in the liver and is found in plasma, liver, intestinal mucosa and other tissues. Six percent to 7% of patients in most surgical populations have an abnormal plasma cholinesterase activity and about 65% of all cases of prolonged neuromuscular blockade following succinylcholine are due to genetic factors. This review focuses on the causes and clinical significance...
Topics
- Anesthesiology
- Cholinesterases
- Female
- Genotype
- Humans
- Isoquinolines
- Male
- Mivacurium
- Neuromuscular Nondepolarizing Agents
- Phenotype
- Prodrugs
- Succinylcholine
