Article
Mivacurium-induced neuromuscular blockade in patients with atypical plasma cholinesterase.
Acta anaesthesiologica Scandinavica - 1 Apr 1993
Ostergaard D, Jensen F S, Jensen E, Skovgaard L T, Viby-Mogensen J
Abstract excerpt
The duration of action of mivacurium was evaluated during a modified neurolept anaesthesia in 17 patients heterozygous for the usual and the atypical plasma cholinesterase (pChe) gene (E1uE1a) and in five patients homozygous for the atypical gene (E1aE1a). The response to train-of-four nerve stim...
Topics
- Adolescent
- Adult
- Aged
- Anesthesia Recovery Period
- Cholinesterases
- Heterozygote
- Homozygote
- Humans
- Isoquinolines
- Middle Aged
- Mivacurium
- Muscle Contraction
- Neostigmine
- Neuromuscular Junction
- Neuromuscular Nondepolarizing Agents
- Phenotype
- Reaction Time
- Synaptic Transmission