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Article

Susceptibility of lipopolysaccharide-responsive and -hyporesponsive ItyS Mice to infection with rough mutants of Salmonella typhimurium.

Infection and immunity - 1 Apr 1996

Mattsby-Baltzer I, Ahlström B, Edebo L, de Man P

Abstract excerpt

The R5 (chemotype Rb) but not the R10 (chemotype Rd) mutant of murine pathogen Salmonella typhimurium 395MS was extremely virulent in intraperitoneal infections of C57BL/10ScCr mice carrying the ityS and lpsD alleles. C57BL/6J (ityS lpsN) and C3H/HeJ (ityR lpsD) mice showed a much higher resistance to the R5 mutant. Further studies were performed with peritoneal macrophages in vitro in order to elucidate...

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Identifiers

PMID: 8606096
DOI: 10.1128/iai.64.4.1321-1327.1996
PMCID: PMC173921

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