Article
Differential myelopoietic responsiveness of BALB/c (Itys) and C.D2 (Ityr) mice to lipopolysaccharide administration and Salmonella typhimurium infection.
Infection and immunity - 1 Apr 1992
Peterson V M, Madonna G S, Vogel S N
Abstract excerpt
Inheritance of the Ityr or the Itys allele of the Ity murine gene confers resistance or increased susceptibility, respectively, to Salmonella typhimurium infection. Recent studies have documented that Ity gene expression may determine net intracellular replication of S. typhimurium by modulating macrophage function. The purpose of this study was to determine if Ity gene expression modulated macrophage stem cell...
Topics
- Animals
- Bone Marrow
- Cell Division
- Colony-Stimulating Factors
- Female
- Genetic Predisposition to Disease
- Granulocytes
- Hematopoiesis
- Lipopolysaccharides
- Macrophages
- Mice