Ity influences the production of IFN-gamma by murine splenocytes stimulated in vitro with Salmonella typhimurium.

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Article

Ity influences the production of IFN-gamma by murine splenocytes stimulated in vitro with Salmonella typhimurium.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 1993

Ramarathinam L, Niesel D W, Klimpel G R

Abstract excerpt

The Ity-Lsh-Bcg genetic locus in the mouse has been documented to confer innate resistance to at least three intracellular pathogens: Salmonella typhimurium, Leishmania donovani, and Mycobacterium. Expression of the resistance gene(s) results in a slower net growth of these pathogens in the retic...

Topics

Animals
Cells, Cultured
Chromosome Mapping
Genes, Dominant
Immunity, Innate
Interferon-gamma
Interleukin-10
Macrophages
Mice
Mice, Inbred Strains
Phenotype
Salmonella Infections, Animal
Salmonella typhimurium
Spleen

Source

Open in PubMed

Identifiers

PMID: 8473743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8473743-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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