Article
Ity influences the production of IFN-gamma by murine splenocytes stimulated in vitro with Salmonella typhimurium.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 1993
Ramarathinam L, Niesel D W, Klimpel G R
Abstract excerpt
The Ity-Lsh-Bcg genetic locus in the mouse has been documented to confer innate resistance to at least three intracellular pathogens: Salmonella typhimurium, Leishmania donovani, and Mycobacterium. Expression of the resistance gene(s) results in a slower net growth of these pathogens in the reticuloendothelial system early postinfection. Although it is clear that the resident macrophages in resistant mice are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
