Article
Linkage analysis with an alternative formulation for the mixed model of inheritance: the finite polygenic mixed model.
Genetics - 1 Dec 1995
Stricker C, Fernando R L, Elston R C
Abstract excerpt
This paper presents an extension of the finite polygenic mixed model of Fernando et al. (1994) to linkage analysis. The finite polygenic mixed model, extended for linkage analysis, leads to a likelihood that can be calculated using efficient algorithms developed for oligogenic models. For compari...
Topics
- Genetic Linkage
- Genotype
- Models, Genetic
- Pedigree
- Recombination, Genetic
