An approximate model of polygenic inheritance.

doi:10.1093/genetics/147.3.1423

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Article

An approximate model of polygenic inheritance.

Genetics - 1 Nov 1997

Lange K

Abstract excerpt

The finite polygenic model approximates polygenic inheritance by postulating that a quantitative trait is determined by n independent, additive loci. The 3n possible genotypes for each person in this model limit its applicability. CANNINGS, THOMPSON, and SKOLNICK suggested a simplified, nongenetic version of the model involving only 2n + 1 genotypes per person. This article shows that this hypergeometric...

Topics

Female
Genetics, Medical
Genotype
Humans
Male
Mathematical Computing
Models, Genetic
Pedigree

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