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Article

Pedigree analysis package vs. MIXD: fitting the mixed model on a large pedigree.

Genetic epidemiology - 1 Jan 1996

Olshen A B, Wijsman E M

Abstract excerpt

Results of a simulation study with two methods of analysis of data simulated under the mixed model on a 232-member pedigree are presented. The programs Pedigree Analysis Package (PAP), which approximate the likelihoods needed in a complex segregation analysis, and MIXD, which uses Monte Carlo Markov chain (MCMC), to estimate likelihoods were used. PAP obtained unbiased estimates of the major locus genotype means...

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Source

Identifiers

PMID: 8647381
DOI: 10.1002/(SICI)1098-2272(1996)13:1<91::AID-GEPI8>3.0.CO;2-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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