Markov chain Monte Carlo segregation and linkage analysis for oligogenic models.

doi:10.1086/515506

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Article

Markov chain Monte Carlo segregation and linkage analysis for oligogenic models.

American journal of human genetics - 1 Sept 1997

Heath S C

Abstract excerpt

A new method for segregation and linkage analysis, with pedigree data, is described. Reversible jump Markov chain Monte Carlo methods are used to implement a sampling scheme in which the Markov chain can jump between parameter subspaces corresponding to models with different numbers of quantitati...

Topics

Computer Simulation
Genetic Linkage
Humans
Markov Chains
Models, Genetic
Monte Carlo Method
Pedigree
Phenotype

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