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Article

Markov chain Monte Carlo segregation and linkage analysis for oligogenic models.

American journal of human genetics - 1 Sept 1997

Heath S C

Abstract excerpt

A new method for segregation and linkage analysis, with pedigree data, is described. Reversible jump Markov chain Monte Carlo methods are used to implement a sampling scheme in which the Markov chain can jump between parameter subspaces corresponding to models with different numbers of quantitative-trait loci (QTL's). Joint estimation of QTL number, position, and effects is possible, avoiding the problems that...

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Identifiers

PMID: 9326339
DOI: 10.1086/515506
PMCID: PMC1715966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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