Article
In vivo protein synthesis in developing hearts of normal and cardiac mutant axolotls (Ambystoma mexicanum).
Cellular & molecular biology research - 1 Jan 1995
Erginel-Unaltuna N, Dube D K, Robertson D R, Lemanski L F
Abstract excerpt
Recessive mutant gene c in axolotls causes a failure of the hearts of affected embryos to function. The mutant hearts (c/c) lack organized sarcomeric myofibrils. The present study was undertaken to determine the overall pattern of in vivo protein synthesis and subsequent accumulation of the newly synthesized proteins for a 24-h period in normal (+/+ or +/c) and cardiac mutant (c/c) axolotl hearts at various...
Topics
- Ambystoma
- Animals
- Gene Expression Regulation
- Genes, Lethal
- Genes, Recessive
- Heart
- Muscle Proteins
- Mutation
- Myocardium
- Myofibrils
