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Article

The cardiac mutant Mexican axolotl is a unique animal model for evaluation of cardiac myofibrillogenesis.

Experimental cell research - 1 May 1999

Zajdel R W, Dube D K, Lemanski L F

Abstract excerpt

Hearts from cardiac mutant Mexican axolotl, Ambystoma mexicanum, do not form organized myofibrils and fail to beat. Though previous biochemical and immunohistochemical experiments showed a possible reduction of cardiac tropomyosin it was not clear that this caused the lack of organized myofibrils in mutant hearts. We used cationic liposomes to introduce both rabbit and chicken tropomyosin protein into whole...

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Source

Identifiers

PMID: 10222147
DOI: 10.1006/excr.1999.4419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The cardiac mutant Mexican axolotl is a unique animal model for evaluation of cardiac myofibrillogenesis.PMID 10222147Read ↗

Immunofluorescent confocal analysis of tropomyosin in developing hearts of normal and cardiac mutant axolotls, Ambystoma mexicanum.Semantic proximity Read ↗

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In vivo protein synthesis in developing hearts of normal and cardiac mutant axolotls (Ambystoma mexicanum).Semantic proximity Read ↗

Tropomodulin expression in developing hearts of normal and cardiac mutant Mexican axolotl.Semantic proximity Read ↗

Immunofluorescent studies on titin and myosin in developing hearts of normal and cardiac mutant axolotls.Semantic proximity Read ↗

Molecular and immunohistochemical analyses of cardiac troponin T during cardiac development in the Mexican axolotl, Ambystoma mexicanum.Semantic proximity Read ↗

Relationship between cardiac protein tyrosine phosphorylation and myofibrillogenesis during axolotl heart development.Semantic proximity Read ↗

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Cardiac myofibril formation is not affected by modification of both N- and C-termini of sarcomeric tropomyosin.Semantic proximity Read ↗

The cardiac mutant gene c in axolotls: cellular, developmental, and molecular studies.Semantic proximity Read ↗

Characterization of a TM-4 type tropomyosin that is essential for myofibrillogenesis and contractile activity in embryonic hearts of the Mexican axolotl.Semantic proximity Read ↗

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