Article
Confocal microscopy of a newly identified protein associated with heart development in the Mexican axolotl.
Cellular & molecular biology research - 1 Jan 1995
Erginel-Unaltuna N, Dube D K, Salsbury K G, Lemanski L F
Abstract excerpt
Recessive mutant gene c for "'cardiac nonfunction" in the mexican axolotl, Ambystoma mexicanum, results in a failure of affected embryos to develop contracting hearts. Mutant embryos survive approximately 4 weeks after fertilization, but eventually die from a lack of circulation. Morphological st...
Topics
- Ambystoma mexicanum
- Amino Acid Sequence
- Amphibian Proteins
- Animals
- Antibodies
- Base Sequence
- Blotting, Western
- Cloning, Molecular
- Culture Media, Conditioned
- DNA, Complementary
- Embryonic and Fetal Development
- Epitopes
- Heart
- Heterozygote
- Homozygote
- Immunohistochemistry
- Liver
- Lung
