Article
Exclusion from proximal 11q of a common gene with megaphenic effect on atopy.
Annals of human genetics - 1 Oct 1995
Watson M, Lawrence S, Collins A, Beasley R, Doull I, Begishvili B, Lampe F, Holgate S T, Morton N E
Abstract excerpt
We have typed three markers on proximal 11q in 131 random families with three or more children studied for atopy. A summary map that includes the FCER1B candidate was constructed. Using a 2-locus disease model, we performed combined segregation and linkage analysis of three models, none of which...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Data Interpretation, Statistical
- Female
- Genetic Linkage
- Genetic Markers
- Heterozygote
- Humans
- Hypersensitivity, Immediate
- Leukocytes
- Lod Score
- Male
- Multiple Endocrine Neoplasia Type 1
- Phosphorylases
- Receptors, IgE
- United Kingdom
