Article
Lack of linkage between atopy and locus 11q13.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 1992
Hizawa N, Yamaguchi E, Ohe M, Itoh A, Furuya K, Ohnuma N, Kawakami Y
Abstract excerpt
Atopy as defined in terms of IgE responsiveness was reported to be controlled by a single gene in British families, and this concept was further supported by a significant linkage between atopy and restriction fragment length polymorphism (RFLP) detected by a DNA probe specific to chromosome 11q13. To confirm this observation in a Japanese population, segregation and linkage analyses were done in four large...
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