Article
Lack of linkage between atopy and locus 11q13.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 1992
Hizawa N, Yamaguchi E, Ohe M, Itoh A, Furuya K, Ohnuma N, Kawakami Y
Abstract excerpt
Atopy as defined in terms of IgE responsiveness was reported to be controlled by a single gene in British families, and this concept was further supported by a significant linkage between atopy and restriction fragment length polymorphism (RFLP) detected by a DNA probe specific to chromosome 11q13. To confirm this observation in a Japanese population, segregation and linkage analyses were done in four large...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Child
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Genetic Linkage
- Humans
- Hypersensitivity
- Immunoglobulin E