Article
Association study of the chromosomal region containing the FCER2 gene suggests it has a regulatory role in atopic disorders.
American journal of respiratory and critical care medicine - 1 Mar 2000
Laitinen T, Ollikainen V, Lázaro C, Kauppi P, de Cid R, Antó J M, Estivill X, Lokki H, Mannila H, Laitinen L A, Kere J
Abstract excerpt
On the basis of studies with animal models, the gene for the low-affinity receptor for immunoglobulin E (IgE) (FCER2, CD23) has been implicated as a candidate for IgE-mediated allergic diseases and bronchial hyperreactivity, or related traits. Given evidence for genetic complexity in atopic disorders, we sought to study two European subpopulations, Finnish and Catalonian. We studied three phenotypic markers: (1)...
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