Article
Linkage and association studies of atopy and the chromosome 11q13 region.
Journal of medical genetics - 1 May 1999
Deichmann K A, Starke B, Schlenther S, Heinzmann A, Sparholt S H, Forster J, Kuehr J
Abstract excerpt
The clinical syndrome atopy is largely determined by genetic factors. In 1989, the first linkage of markers within and flanking the chromosomal region 11q13 and atopy was reported. In the following years, the gene coding for the beta chain of the high affinity IgE receptor was localised to this region and two polymorphisms in this gene have been shown to be associated with the atopic phenotype. We investigated...
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