Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antigenic variation and the within-host dynamics of parasites.

Proceedings of the National Academy of Sciences of the United States of America - 6 Feb 1996

Antia R, Nowak M A, Anderson R M

Abstract excerpt

Many parasites exhibit antigenic variation within their hosts. We use mathematical models to investigate the dynamical interaction between an antigenically varying parasite and the host's immune system. The models incorporate antigenic variation in the parasite population and the generation of immune responses directed against (i) antigens specific to individual parasite variants and (ii) antigens common to all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibody Formation
Share to Antigens
Share to Cross Reactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Host-Parasite Interactions

Share to Mathematics

Share to Models, Theoretical

Share to Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 8577773
DOI: 10.1073/pnas.93.3.985
PMCID: PMC40016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antigenic variation and the within-host dynamics of parasites.PMID 8577773Read ↗

The effect of host heterogeneity and parasite intragenomic interactions on parasite population structure.Semantic proximity Read ↗

A perspective on clonal phenotypic (antigenic) variation in protozoan parasites.Semantic proximity Read ↗

Population structure of pathogens: the role of immune selection.Semantic proximity Read ↗

Multi-scale immune selection and the transmission-diversity feedback of <i>Plasmodium falciparum</i> malariaSemantic proximity Read ↗

Pathogen evolution and the immunological niche.Semantic proximity Read ↗

Evolutionary pattern of intra-host pathogen antigenic drift: effect of cross-reactivity in immune response.Semantic proximity Read ↗

Antigenic diversity, transmission mechanisms, and the evolution of pathogens.Semantic proximity Read ↗

Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.Semantic proximity Read ↗

Acute or Chronic? Within‐Host Models with Immune Dynamics, Infection Outcome, and Parasite EvolutionSemantic proximity Read ↗

Identifying the molecular basis of host-parasite coevolution: merging models and mechanisms.Semantic proximity Read ↗

An antigenic diversification threshold for falciparum malaria transmission at high endemicitySemantic proximity Read ↗

Emerging challenges in understanding trypanosome antigenic variationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.