Acute or Chronic? Within‐Host Models with Immune Dynamics, Infection Outcome, and Parasite Evolution

Abstract excerpt

There is ample theoretical and experimental evidence that virulence evolution depends on the immune response of the host. In this article, we review a number of recent studies that attempt to explicitly incorporate the dynamics of the immune system (instead of merely representing it by a single black box parameter) in models for the evolution of parasite virulence. A striking observation is that the type of...

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