Article
A perspective on clonal phenotypic (antigenic) variation in protozoan parasites.
Parasitology - 1 Jan 2002
Turner C M R
Abstract excerpt
Intra-clonal phenotypic (antigenic) variation is used by many pathogens to evade the consequences of immune-mediated killing by mammalian hosts. In this substantially theoretical article, I emphasise that antigenic variation (sensu stricto) involves no change in genotype; its importance as a mechanism for promoting pathogen transmission and its polyphyletic origin. From a functional perspective, antigenic...
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