Population structure of pathogens: the role of immune selection.

doi:10.1016/s0169-4758(99)01559-8

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Article

Population structure of pathogens: the role of immune selection.

Parasitology today (Personal ed.) - 1 Dec 1999

Gupta S, Anderson R M

Abstract excerpt

Sunetra Gupta and Roy Anderson discuss how the balance between host immune responses against conserved and variable antigens shapes the population structure of pathogens. At one extreme, immune selection against polymorphic determinants can cause pathogen populations to self-organize spontaneously into discrete antigenic types that may either be maintained over long periods or undergo cyclical or chaotic...

Topics

Alleles
Animals
Antigenic Variation
Dengue
Dengue Virus
HIV
HIV Infections
Hepatitis B
Hepatitis B virus
Humans
Linkage Disequilibrium
Malaria, Falciparum
Meningitis, Meningococcal
Models, Immunological
Neisseria meningitidis
Nonlinear Dynamics
Plasmodium falciparum

Source

Open in PubMed

Identifiers

PMID: 10557151
DOI: 10.1016/s0169-4758(99)01559-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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