Article
Interaction of the lipoprotein lipase asparagine 291-->serine mutation with body mass index determines elevated plasma triacylglycerol concentrations: a study in hyperlipidemic subjects, myocardial infarction survivors, and healthy adults.
Journal of lipid research - 1 Oct 1995
Fisher R M, Mailly F, Peacock R E, Hamsten A, Seed M, Yudkin J S, Beisiegel U, Feussner G, Miller G, Humphries S E
Abstract excerpt
A mutation in the lipoprotein lipase (LPL) gene, resulting in the substitution of asparagine by serine at residue 291 (LPL-S291), was found to occur in young survivors of a myocardial infarction from Sweden, combined hyperlipidemic subjects from the United Kingdom, and type III hyperlipidemic sub...
Topics
- Adolescent
- Adult
- Aged
- Amino Acid Sequence
- Arginine
- Base Sequence
- Body Mass Index
- Case-Control Studies
- Female
- Genetic Variation
- Humans
- Hyperlipidemias
- Lipoprotein Lipase
- Male