The -1131T-->C polymorphism in the apolipoprotein A5 gene is associated with postprandial hypertriacylglycerolemia; elevated small, dense LDL concentrations; and oxidative stress in nonobese Korean men.

Abstract excerpt

BACKGROUND: Apolipoprotein A5 plays an important role in modulating triacylglycerol metabolism in experimental animal models. OBJECTIVE: The objective was to determine associations of the common apolipoprotein A5 gene (APOA5) -1131T-->C polymorphism with postprandial lipemic response and other cardiovascular disease risk factors in humans. DESIGN: Healthy, nonobese subjects [n = 158; mean (+/-SEM) age: 33.8 +/-...

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