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Article

[Frequent mutation doubles the risk of ischemic heart disease in women].

Ugeskrift for laeger - 29 Jun 1998

Wittrup H H, Tybjaerg-Hansen A, Abildgaard S, Steffensen R, Schnohr P, Nordestgaard B G

Abstract excerpt

Lipoprotein lipase degrades triglycerides in plasma and as a by-product produces HDL particles. Genetic variation in lipoprotein lipase may therefore affect cardiovascular risk. We tested 9214 men and women from a general population sample and 948 patients with ischaemic heart disease for the Asn291Ser substitution in lipoprotein lipase. The allele frequency in the general population was 0.024 and 0.026 for women...

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Source

Identifiers

PMID: 9659837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Frequent mutation doubles the risk of ischemic heart disease in women].PMID 9659837Read ↗

A common substitution (Asn291Ser) in lipoprotein lipase is associated with increased risk of ischemic heart disease.Semantic proximity Read ↗

A common mutation in lipoprotein lipase confers a 2-fold increase in risk of ischemic cerebrovascular disease in women but not in men.Semantic proximity Read ↗

A common mutation in the lipoprotein lipase gene (N291S) alters the lipoprotein phenotype and risk for cardiovascular disease in patients with familial hypercholesterolemia.Semantic proximity Read ↗

Mutations in the lipoprotein lipase gene associated with ischemic heart disease in men. The Copenhagen city heart study.Semantic proximity Read ↗

Functional variants in the lipoprotein lipase gene and risk cardiovascular disease.Semantic proximity Read ↗

Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis.Semantic proximity Read ↗

Combined analysis of six lipoprotein lipase genetic variants on triglycerides, high-density lipoprotein, and ischemic heart disease: cross-sectional, prospective, and case-control studies from the Copenhagen City Heart Study.Semantic proximity Read ↗

Heterozygous lipoprotein lipase deficiency: frequency in the general population, effect on plasma lipid levels, and risk of ischemic heart disease.Semantic proximity Read ↗

Lipoprotein lipase gene variants and risk of coronary disease: a quantitative analysis of population-based studies.Semantic proximity Read ↗

Common mutations of the lipoprotein lipase gene and their clinical significance.Semantic proximity Read ↗

The common mutations in the lipoprotein lipase gene in Italy: effects on plasma lipids and angiographically assessed coronary atherosclerosis.Semantic proximity Read ↗

Lipoprotein lipase genetic variation and gender-specific ischemic cerebrovascular disease risk.Semantic proximity Read ↗

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