Article
Delayed clearance of postprandial large TG-rich particles in normolipidemic carriers of LPL Asn291Ser gene variant.
Journal of lipid research - 1 Sept 1999
Mero N, Suurinkeroinen L, Syvänne M, Knudsen P, Yki-Järvinen H, Taskinen M R
Abstract excerpt
The carrier frequency of Asn291Ser polymorphism of the lipoprotein lipase (LPL) gene is 4;-6% in the Western population. Heterozygotes are prone to fasting hypertriglyceridemia and low high density lipoprotein (HDL) cholesterol concentrations especially when secondary factors are superimposed on the genetic defect. We studied the LPL Asn291Ser gene variant as a modulator of postprandial lipemia in heterozygote...
Topics
- Adult
- Apolipoprotein B-100
- Apolipoprotein B-48
- Apolipoproteins B
- Base Sequence
- Blood Glucose
- Cholesterol
- DNA Primers
- Dietary Fats
- Fasting
- Female