Article
Lipoprotein lipase variants D9N and N291S are associated with increased plasma triglyceride and lower high-density lipoprotein cholesterol concentrations: studies in the fasting and postprandial states: the European Atherosclerosis Research Studies.
Circulation - 5 Aug 1997
Gerdes C, Fisher R M, Nicaud V, Boer J, Humphries S E, Talmud P J, Faergeman O
Abstract excerpt
BACKGROUND: Variations at the DNA level with moderate effects on biochemical variables may be important for the occurrence of disease at the population level, if they are common. Two mutations in the LPL gene, N9 and S291, are associated with variation in fasting plasma concentrations of HDL chol...
Topics
- Adolescent
- Adult
- Alleles
- Arteriosclerosis
- Case-Control Studies
- Cholesterol, HDL
- Eating
- Fasting
- Female
- Gene Frequency
- Genetic Variation
- Humans
- Lipoprotein Lipase
- Male