The cellular effects of E2F overexpression.

doi:10.1007/978-3-642-79910-5_4

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Article

The cellular effects of E2F overexpression.

Current topics in microbiology and immunology - 1 Jan 1996

Adams P D, Kaelin W G

Abstract excerpt

The product of the retinoblastoma tumor-suppressor gene (RB) is a ubiquitously expressed, 105-kDa nuclear phosphoprotein (pRB). The pRB protein negatively regulates the cellular G1/S phase transition, and it is at this point in the cell cycle that it is thought to play its role as a tumor suppres...

Topics

Animals
Apoptosis
Carrier Proteins
Cell Cycle
Cell Cycle Proteins
Cell Transformation, Neoplastic
DNA-Binding Proteins
E2F Transcription Factors
E2F1 Transcription Factor
E2F4 Transcription Factor
Humans
Mutation
Retinoblastoma-Binding Protein 1
Transcription Factor DP1
Transcription Factors
Transforming Growth Factor beta
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 8575214
DOI: 10.1007/978-3-642-79910-5_4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8575214-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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