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Article

Alterations in G1/S cell-cycle control contributing to carcinogenesis.

Annals of the New York Academy of Sciences - 29 Dec 1997

Kaelin W G

Abstract excerpt

Mutations involving the retinoblastoma tumor-suppressor gene (RB-1) have been described in a variety of human neoplasms. In addition, many tumors that retain a wild-type RB-1 allele harbor mutations that indirectly impair the function of the RB-1 gene product (pRB). pRB is a nuclear protein that regulates cell-cycle progression and, in at least certain tissues, differentiation. The former has been linked to its...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9616737
DOI: 10.1111/j.1749-6632.1997.tb48589.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Alterations in G1/S cell-cycle control contributing to carcinogenesis.PMID 9616737Read ↗

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