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Article

Induction of S-Phase Entry by E2F Transcription Factors Depends on Their Nuclear Localization

1 Sept 1997

Abstract excerpt

The E2F transcription factors are essential for regulating the correct timing of activation of several genes whose products are implicated in cell proliferation and DNA replication. The E2Fs are targets for negative regulation by the retinoblastoma protein family, which includes pRB, p107, and p130, and they are in a pathway that is frequently found altered in human cancers. There are five members of the E2F...

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Identifiers

PMID: 9271426
DOI: 10.1128/mcb.17.9.5508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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