Chromatin structure and imprinting: developmental control of DNase-I sensitivity in the mouse insulin-like growth factor 2 gene.

doi:10.1002/dvg.1020170309

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Article

Chromatin structure and imprinting: developmental control of DNase-I sensitivity in the mouse insulin-like growth factor 2 gene.

Developmental genetics - 1 Jan 1995

Feil R, Handel M A, Allen N D, Reik W

Abstract excerpt

The insulin-like growth factor 2 (Igf2) gene on distal mouse chromosome 7 is expressed predominantly from the paternal allele. In previous studies we identified two regions of paternal allele-specific methylation; one at approximately 3 kb upstream of promoter 1, and a second in the 3', coding po...

Topics

Alleles
Animals
Cell Line
Chromatin
Deoxyribonuclease I
Female
Gene Expression Regulation, Developmental
Genomic Imprinting
Insulin-Like Growth Factor II
Male
Methylation
Mice
Mice, Inbred C57BL
Promoter Regions, Genetic

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