Article
Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes.
Development (Cambridge, England) - 1 Oct 1994
Feil R, Walter J, Allen N D, Reik W
Abstract excerpt
The Insulin-like growth factor 2 (Igf2) and H19 genes are reciprocally imprinted and closely linked. Igf2 encodes a fetal growth-factor and is predominantly expressed from the paternal allele, while H19 is expressed from the maternal allele and encodes a transcript which may downregulate cellular...
Topics
- Alleles
- Animals
- Base Sequence
- Choroid Plexus
- DNA
- DNA Primers
- Female
- Genomic Imprinting
- Insulin-Like Growth Factor II
- Male
- Methylation
- Mice
- Molecular Sequence Data
- Muscle Proteins
- Polymerase Chain Reaction
- Pregnancy
- RNA, Long Noncoding
- RNA, Untranslated