Article
Heparin and the phenotype of adult human vascular smooth muscle cells.
In vitro cellular & developmental biology. Animal - 1 Oct 1995
Sorger T, Friday N, Yang L D, Levine E M
Abstract excerpt
To study mechanisms controlling growth and phenotype in human vascular smooth muscle cells, we established culture conditions under which these cells proliferate rapidly and achieve life-spans of 50-60 population doublings. In medium containing heparin and heparin-binding growth factors, growth rate and life-span of human vascular smooth muscle cells increased more than 50% relative to cultures with neither...
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