Article
Heparin and the phenotype of adult human vascular smooth muscle cells.
In vitro cellular & developmental biology. Animal - 1 Oct 1995
Sorger T, Friday N, Yang L D, Levine E M
Abstract excerpt
To study mechanisms controlling growth and phenotype in human vascular smooth muscle cells, we established culture conditions under which these cells proliferate rapidly and achieve life-spans of 50-60 population doublings. In medium containing heparin and heparin-binding growth factors, growth r...
Topics
- Actin Cytoskeleton
- Actins
- Adult
- Animals
- Base Sequence
- Cell Culture Techniques
- Cell Division
- Cells, Cultured
- Extracellular Matrix
- Glycosaminoglycans
- Growth Substances
- Heparin
- Humans
- Hyaluronic Acid
- Molecular Sequence Data
- Muscle, Smooth, Vascular
- Oligonucleotide Probes
- Phenotype